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302 Found - e10e4.com
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Date: Sun, 18 May 2025 05:43:16 GMT
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200 OK - https://bindwell.ai
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HTTP Code 200 OK

200 OK is a standard successful HTTP server response. It means that the client’s request (e.g., from a browser) was successfully processed, and the server is delivering the requested data.

When is Code 200 used?

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The user receives content without errors, and the page or application functions properly. If Code 200 is accompanied by data, the browser or program processes and displays it to the user.

GET / HTTP/1.1
Host: e10e4.com
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<!DOCTYPE html><html lang="en"> <head><meta charset="utf-8"><link rel="icon" type="image/svg+xml" href="/_astro/favicon.dULsUXfS.svg"><meta name="viewport" content="width=device-width"><meta name="generator" content="Astro v5.3.0"><title>Bindwell</title><style>@charset "UTF-8";:root{font-size:22px;--col-background: #EEFFF6;--col-foreground: #000100;--col-primary: #23BA7D;--col-primary-overlay: #23BA7D30;--col-protein: var(--col-foreground);--col-protein-outline: var(--col-primary)}html{scroll-behavior:smooth}*{box-sizing:border-box}body{font-family:EB Garamond,sans-serif;text-rendering:optimizeLegibility;background-color:var(--col-background);color:var(--col-foreground)}@font-face{font-family:EB Garamond;src:url(/fonts/EBGaramond-Regular.woff2) format("woff2");font-weight:400;font-style:normal}@font-face{font-family:EB Garamond;src:url(/fonts/EBGaramond-Italic.woff2) format("woff2");font-weight:400;font-style:italic}@font-face{font-family:EB Garamond;src:url(/fonts/EBGaramond-Bold.woff2) format("woff2");font-weight:700}@font-face{font-family:EB Garamond;src:url(/fonts/EBGaramond-BoldItalic.woff2) format("woff2");font-weight:700;font-style:italic}span[data-astro-cid-tvrurpns]{color:var(--col-foreground);font-size:var(--size, inherit);font-style:italic;font-weight:800;font-variation-settings:"ital" 1,"wght" 800;font-feature-settings:"swsh" on;filter:drop-shadow(.15em -.1em 0 var(--col-primary))}nav[data-astro-cid-3zbxo6iv]{position:absolute;top:24px;left:24px;font-size:36px;background-color:var(--col-background);color:var(--col-foreground)}nav[data-astro-cid-3zbxo6iv] a[data-astro-cid-3zbxo6iv]{text-decoration:none;color:inherit}body{margin:144px auto 0;padding:0 2ch;max-width:90ch}.type{font-family:EB Garamond,serif;font-feature-settings:"calt";font-size:1rem;line-height:1.3;text-wrap:pretty}.type .oldstyle-nums{font-variant-numeric:oldstyle-nums}.type .small-caps{font-variant:small-caps;letter-spacing:.1em}.type em{font-style:italic}.type strong{font-weight:800}.type strong em,.type em strong{font-style:normal;font-variant:small-caps;letter-spacing:.1em}.type i{font-style:italic}.type a{color:inherit;text-decoration:var(--col-primary) underline}.type blockquote{font-style:italic}.type blockquote cite,.type blockquote figcaption{display:block;margin-top:.5em;text-align:right}.type blockquote cite:before,.type blockquote figcaption:before{content:"— "}.type h1,.type h2,.type h3,.type h4,.type h5,.type h6{text-align:left;font-weight:400;font-style:italic}.type h2{margin-top:3rem;margin-bottom:1rem}.type h3{margin-top:2rem;margin-bottom:.75rem}.type img{max-width:100%;height:auto}
main[data-astro-cid-j7pv25f6]{margin-bottom:144px}h1[data-astro-cid-j7pv25f6]{font-size:64px;margin-bottom:0}.cta-row[data-astro-cid-j7pv25f6]{display:flex;flex-direction:row;flex-wrap:wrap;gap:2ch}.cta-row[data-astro-cid-j7pv25f6] a[data-astro-cid-j7pv25f6]{display:flex;flex-direction:row;align-items:center;gap:.5ch;text-decoration:none;border-radius:.5em;padding:.25em .5em;color:var(--col-primary)}.cta-row[data-astro-cid-j7pv25f6] a[data-astro-cid-j7pv25f6]:hover{background-color:var(--col-primary-overlay)}.protein-demo[data-astro-cid-j7pv25f6]{display:flex;flex-direction:row;flex-wrap:wrap;gap:2ch}.protein-demo[data-astro-cid-j7pv25f6] div[data-astro-cid-j7pv25f6]{flex:1;min-width:300px}.protein-demo[data-astro-cid-j7pv25f6] h3[data-astro-cid-j7pv25f6]{font-size:30px}.protein-demo[data-astro-cid-j7pv25f6] .traditional-protein[data-astro-cid-j7pv25f6]{--col-protein: var(--col-background);--col-protein-outline: var(--col-foreground)}
</style><script type="module" src="/_astro/page.V2R8AmkL.js"></script></head> <body>  <main class="type" data-astro-cid-j7pv25f6> <h1 data-astro-cid-j7pv25f6><span style data-astro-cid-tvrurpns>Bindwell</span> </h1> <p data-astro-cid-j7pv25f6>
We're building better pesticides using AI. The agrochemical industry is
      stagnant, it's time for a change.<br data-astro-cid-j7pv25f6>
Backed by
<a href="https://ycombinator.com" data-astro-cid-j7pv25f6>Y Combinator</a>,
<a href="https://character.vc" data-astro-cid-j7pv25f6>Character</a>,
<a href="https://paulgraham.com" data-astro-cid-j7pv25f6>Paul Graham</a>, and others.
</p> <blockquote data-astro-cid-j7pv25f6>
The founders [of Bindwell] will probably do alright. They're smart and
      have a good idea.
<cite data-astro-cid-j7pv25f6> <a href="https://x.com/paulg/status/1892727438318436540" data-astro-cid-j7pv25f6>
Paul Graham, on X
</a> </cite> </blockquote> <p class="cta-row" data-astro-cid-j7pv25f6> <a href="/contact" data-astro-prefetch data-astro-cid-j7pv25f6>
Get in touch
<svg width="1em" height="1em" data-astro-cid-j7pv25f6="true" data-icon="mdi:arrow-right">   <symbol id="ai:mdi:arrow-right" viewBox="0 0 24 24"><path fill="currentColor" d="M4 11v2h12l-5.5 5.5l1.42 1.42L19.84 12l-7.92-7.92L10.5 5.5L16 11z"/></symbol><use href="#ai:mdi:arrow-right"></use>  </svg> </a> </p> <h2 data-astro-cid-j7pv25f6>The team</h2> <p data-astro-cid-j7pv25f6>
We’re Navvye Anand (Caltech) and Tyler Rose (Wolfram Research), a scrappy
      duo of engineers who met at the Wolfram Summer Research Program in June
      2023. We’re from India and China, respectively, and both close to
      farmlands in our countries. United by our passion for tackling global
      problems, we dropped out of college and started Bindwell to transform the
      old agrochemical industry.
</p> <p data-astro-cid-j7pv25f6>
We’re joined by <a href="https://maxniederman.com" data-astro-cid-j7pv25f6>Max Niederman</a>, a
      prodigious hacker and open source contributor who dropped out of a math
      degree at Reed College. Max is relentlessly curious about everything from
      graphic design to robotics, and his passion for solving challenging
      problems made him a perfect fit for our team.
</p> <h2 data-astro-cid-j7pv25f6>The problem</h2> <p data-astro-cid-j7pv25f6> <strong data-astro-cid-j7pv25f6>Pesticides are failing us:</strong> Their usage has doubled since 2000,
      even though farmland has decreased. Yet, we still lose 20-40% of crops to pests.
</p> <p data-astro-cid-j7pv25f6> <strong data-astro-cid-j7pv25f6>Resistance makes things worse:</strong> Pests evolve resistance, forcing
      farmers to use even more pesticides to get the same results. This creates a
      vicious cycle of increasing resistance and collateral damage.
</p> <p data-astro-cid-j7pv25f6> <strong data-astro-cid-j7pv25f6>Innovation is stagnant:</strong> Since the 2010s, fewer than 40 new
      active ingredients have been introduced. Most "new" pesticides are just minor
      tweaks of existing chemicals.
</p> <p data-astro-cid-j7pv25f6> <strong data-astro-cid-j7pv25f6>Industry left behind:</strong> AI has revolutionized drug discovery;
      pesticide discovery is overdue for the same transformation because the underlying
      biochemistry is similar.
</p> <p data-astro-cid-j7pv25f6> <strong data-astro-cid-j7pv25f6>Making better pesticides is hard:</strong> The ideal pesticide kills
      only the target pest and nothing else—current solutions fail at this.
</p> <h2 data-astro-cid-j7pv25f6>Our solution</h2> <p data-astro-cid-j7pv25f6>We use AI to build better pesticides.</p> <p data-astro-cid-j7pv25f6>
Because pesticide discovery is a search problem, speed is key: In mere
      seconds, our AI models give us biological assays that would have
      traditionally taken days—completely changing the game for pesticide
      discovery.
</p> <p data-astro-cid-j7pv25f6>We've built these AI models so far:</p> <ul data-astro-cid-j7pv25f6> <li data-astro-cid-j7pv25f6>
Foldwell: our AlphaFold replacement that’s 4× faster, used to identify
        target structures.
</li> <li data-astro-cid-j7pv25f6>
PLAPT: Insanely fast open-source protein-ligand interaction model that
        can scan every synthesized compound known to man in just 6 hours.
</li> <li data-astro-cid-j7pv25f6>
APPT: State-of-the-art protein-protein interaction model for
        biopesticide screening, outperforms existing models by 1.7× on
<a href="https://zlab.wenglab.org/benchmark/" data-astro-cid-j7pv25f6>
Affinity Benchmark V5.5</a>.
</li> </ul> <p data-astro-cid-j7pv25f6>
We’re currently making our first pesticide, more to come soon...
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