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301 Moved Permanently - sielc.com
HTTP Status: 301
User-Agent: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; [email protected])
Cache-Control: private
Location: https://sielc.com:443/
Content-Length: 0
Date: Mon, 19 May 2025 12:12:54 GMT
Content-Type: text/html; charset=UTF-8
HTTP Code 301 Moved Permanently
301 Moved Permanently means that the requested resource has been permanently moved to a new URL. All future requests should use the new address.
When is Code 301 used?
- When changing a website domain
- When modifying URL structures
- When setting up redirects for SEO
What does Code 301 mean for the user?
The browser will automatically redirect the user to the new address, and search engines will update their indexes.
200 OK - https://sielc.com:443/
HTTP Status: 200
User-Agent: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; [email protected])
date: Mon, 19 May 2025 12:12:54 GMT
server: Apache
last-modified: Mon, 19 May 2025 02:29:26 GMT
vary: Accept-Encoding
content-type: text/html; charset=UTF-8
via: 1.1 google
Alt-Svc: h3=":443"; ma=2592000,h3-29=":443"; ma=2592000
Transfer-Encoding: chunked
HTTP Code 200 OK
200 OK is a standard successful HTTP server response. It means that the client’s request (e.g., from a browser) was successfully processed, and the server is delivering the requested data.
When is Code 200 used?
- When loading a web page
- When successfully receiving an API response
- When processing a form or another HTTP request
What does Code 200 mean for the user?
The user receives content without errors, and the page or application functions properly. If Code 200 is accompanied by data, the browser or program processes and displays it to the user.
GET / HTTP/1.1 Host: sielc.com Accept: */* User-Agent: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; [email protected])
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Newcrom B
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Newcrom BH
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Newcrom CN2
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Solid-Core Primesep SB
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PEI
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Alltesta™ Isocratic Automated Analyzer
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Alltesta™ Gradient Automated Analyzer
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Cromite™ HPLC System
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Alltesta™ Mini Autosampler
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Alltesta™ Mini High-Pressure Switching Valve
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Alltesta™ Mini LHS (Liquid Handling Station)
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Alltesta™ Mini Syringe Pump
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Alltesta™ Mini UV-Vis Detector
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Alltesta™ Power Tower
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Samplify™ Automated Sampling System
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Software – HPLC.cloud
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Autosampler Schematics
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Column Hardware
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Filters
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Fittings
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PEEK Tubing
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PTFE Tubing
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Back pressure regulator
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Vials for samples
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Analytical Columns
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Capillary Columns
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Preparative Columns
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High Pressure HPLC Fittings
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Ultra High Pressure HPLC Fittings
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Primesep Guard Columns
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Newcrom Guard Columns
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Obelisc Guard Columns
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BIST™ Guard Columns
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Cannsep Guard Columns
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Legacy Guard Columns
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SHARC Guard Columns
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Lipak Guard Columns
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OligoMg Guard Columns
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Promix Guard Columns
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<a href='https://sielc.com/single-ended-column' >
Single-Ended HPLC Column
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<a href='https://sielc.com/lipids' >
Lipids
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<a href='https://sielc.com/oligonucleotides-mg' >
Oligonucleotides
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<a href='https://sielc.com/bridge-ion-separation-technology-or-bist' >
BIST™
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<a href='https://sielc.com/cannabis-analysis' >
Cannabis Analysis by HPLC
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<a href='https://sielc.com/Technology_FlipLC' >
FlipLC™
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HILIC
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<a href='https://sielc.com/Technology_InorganicAnalysis' >
Inorganic Analysis
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<a href='https://sielc.com/Technology_RetentionOfPolarCompounds' >
Polar Compounds
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<a href='https://sielc.com/prep' >
Preparative HPLC Service
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<a href='https://sielc.com/Technology_Peptides' >
Proteins/Peptides
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<a href='https://sielc.com/Technology_Peptides_Selectivity' >
Selectivity
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<a href='https://sielc.com/Technology_SmallMolecules' >
Small Molecules
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<a href='https://sielc.com/Technology_solid-core' >
Solid-Core
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<a href='https://sielc.com/Technology_SwitchPhase' >
Switch Phase
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</ul></div><div class='menu' data-parent_id='38464' data-parents='3463216'><h4>Inorganic Analysis</h4><ul>
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<a href='https://sielc.com/Technology_AlternativeIonChromatography' >
Ion Chromatography
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<a href='https://sielc.com/Technology_OrganicInorganic' >
Organic/Inorganic
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<a href='https://sielc.com/Technology_Peptides_AlternativeSelectivity' >
Alternative Selectivity
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<a href='https://sielc.com/Technology_Peptides_Digest' >
Digest
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<a href='https://sielc.com/Technology_Peptides_GradientTypes' >
Gradient Types
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<a href='https://sielc.com/Technology_Peptides_Promix' >
Promix Technology
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<a href='https://sielc.com/Technology_Peptides_Selectivity' >
Selectivity
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<li id="menu-item-3557267" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-3557267"><a href="https://sielc.com/oligo">Oligo</a>
<ul class="sub-menu">
<li id="menu-item-3557250" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3557250"><a href="https://sielc.com/product-oligomg">OligoMg</a></li>
</ul>
</li>
</ul>
</li>
<li id="menu-item-3543643" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-3543643"><a href="https://sielc.com/devices">Devices</a>
<ul class="sub-menu">
<li id="menu-item-3560186" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-3560186"><a href="https://sielc.com/product/alltesta-isocratic-automated-analyzer">Alltesta™ Isocratic Automated Analyzer</a></li>
<li id="menu-item-3552511" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3552511"><a href="https://sielc.com/alltesta-gradient-automated-analyzer">Alltesta™ Gradient Automated Analyzer</a></li>
<li id="menu-item-3553297" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3553297"><a href="https://sielc.com/alltesta-cromite-analyzer">Cromite™ HPLC System</a></li>
<li id="menu-item-3552515" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-has-children menu-item-3552515"><a href="https://sielc.com/product/alltesta-autosampler">Alltesta™ Mini Autosampler</a>
<ul class="sub-menu">
<li id="menu-item-3547178" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3547178"><a href="https://sielc.com/autosampler-schematics">Autosampler Schematics</a></li>
</ul>
</li>
<li id="menu-item-3552518" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3552518"><a href="https://sielc.com/product/alltesta-high-pressure-switching-valve">Alltesta™ Mini High-Pressure Switching Valve</a></li>
<li id="menu-item-3554099" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3554099"><a href="https://sielc.com/alltesta-lhs">Alltesta™ Mini LHS (Liquid Handling Station)</a></li>
<li id="menu-item-3552523" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3552523"><a href="https://sielc.com/product/alltesta-syringe-pump">Alltesta™ Mini Syringe Pump</a></li>
<li id="menu-item-3552522" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3552522"><a href="https://sielc.com/product/alltesta-mini-uv-vis-detector">Alltesta™ Mini UV-Vis Detector</a></li>
<li id="menu-item-3552514" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3552514"><a href="https://sielc.com/product/alltesta-power-tower">Alltesta™ Power Tower</a></li>
<li id="menu-item-3558400" class="menu-item menu-item-type-post_type menu-item-object-product menu-item-3558400"><a href="https://sielc.com/samplify-automated-sampling-system">Samplify™ Automated Sampling System</a></li>
<li id="menu-item-3544633" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3544633"><a href="https://sielc.com/software-hplc-cloud">Software – HPLC.cloud</a></li>
</ul>
</li>
<li id="menu-item-38523" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38523"><a href="https://sielc.com/Services_CustomPhases">Custom Phases</a></li>
<li id="menu-item-3544643" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-3544643"><a href="https://sielc.com/fluidics">Fluidics</a>
<ul class="sub-menu">
<li id="menu-item-38524" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-38524"><a href="https://sielc.com/Column_Hardware">Column Hardware</a>
<ul class="sub-menu">
<li id="menu-item-38526" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38526"><a href="https://sielc.com/Column_Hardware_Analytical">Analytical Columns</a></li>
<li id="menu-item-38525" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38525"><a href="https://sielc.com/Column_Hardware_Capillary">Capillary Columns</a></li>
<li id="menu-item-3545255" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3545255"><a href="https://sielc.com/Column_Hardware_Preparative">Preparative Columns</a></li>
</ul>
</li>
<li id="menu-item-3544652" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3544652"><a href="https://sielc.com/filters">Filters</a></li>
<li id="menu-item-38530" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-38530"><a href="https://sielc.com/Products_Fittings">Fittings</a>
<ul class="sub-menu">
<li id="menu-item-38528" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38528"><a href="https://sielc.com/products_fittings_hp">High Pressure HPLC Fittings</a></li>
<li id="menu-item-38529" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38529"><a href="https://sielc.com/Products_Fittings_UHP">Ultra High Pressure HPLC Fittings</a></li>
</ul>
</li>
<li id="menu-item-3552979" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-3552979"><a href="/product/peek-tubing">PEEK Tubing</a></li>
<li id="menu-item-3552980" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-3552980"><a href="/product/ptfe-tubing">PTFE Tubing</a></li>
<li id="menu-item-3545709" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3545709"><a href="https://sielc.com/backpressure-regulator-for-hplc">Back pressure regulator</a></li>
<li id="menu-item-3545535" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3545535"><a href="https://sielc.com/vials">Vials for samples</a></li>
</ul>
</li>
<li id="menu-item-38521" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-38521"><a href="https://sielc.com/Products_GuardColumns">Guard Columns</a>
<ul class="sub-menu">
<li id="menu-item-38603" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38603"><a href="https://sielc.com/Products_GuardColumns_Primesep">Primesep Guard Columns</a></li>
<li id="menu-item-3505957" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3505957"><a href="https://sielc.com/Products_GuardColumns_Newcrom">Newcrom Guard Columns</a></li>
<li id="menu-item-38611" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38611"><a href="https://sielc.com/Products_GuardColumns_Obelisc">Obelisc Guard Columns</a></li>
<li id="menu-item-3560651" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560651"><a href="https://sielc.com/products_guardcolumns_bist">BIST™ Guard Columns</a></li>
<li id="menu-item-3560662" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560662"><a href="https://sielc.com/products_guardcolumns_cannsep">Cannsep Guard Columns</a></li>
<li id="menu-item-3560658" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560658"><a href="https://sielc.com/products_guardcolumns_Legacy">Legacy Guard Columns</a></li>
<li id="menu-item-3560672" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560672"><a href="https://sielc.com/products_guardcolumns_sharc">SHARC Guard Columns</a></li>
<li id="menu-item-3560673" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560673"><a href="https://sielc.com/products_guardcolumns_Lipak">Lipak Guard Columns</a></li>
<li id="menu-item-3560686" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560686"><a href="https://sielc.com/products_guardcolumns_oligomg">OligoMg Guard Columns</a></li>
<li id="menu-item-38607" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38607"><a href="https://sielc.com/Products_GuardColumns_Promix">Promix Guard Columns</a></li>
</ul>
</li>
<li id="menu-item-3556273" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-3556273"><a href="https://sielc.com/product-category/mobile-phases">Mobile Phases</a></li>
</ul>
</li>
<li id="menu-item-3463216" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-3463216"><a>Technology</a>
<ul class="sub-menu">
<li id="menu-item-3560609" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560609"><a href="https://sielc.com/single-ended-column">Single-Ended HPLC Column</a></li>
<li id="menu-item-3559266" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3559266"><a href="https://sielc.com/lipids">Lipids</a></li>
<li id="menu-item-3558780" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3558780"><a href="https://sielc.com/oligonucleotides-mg">Oligonucleotides</a></li>
<li id="menu-item-3551908" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-3551908"><a href="https://sielc.com/bridge-ion-separation-technology-or-bist">BIST™</a></li>
<li id="menu-item-3467720" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3467720"><a href="https://sielc.com/cannabis-analysis">Cannabis Analysis by HPLC</a></li>
<li id="menu-item-3536793" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3536793"><a href="https://sielc.com/Technology_FlipLC">FlipLC™</a></li>
<li id="menu-item-38468" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38468"><a href="https://sielc.com/Technology_HILIC">HILIC</a></li>
<li id="menu-item-38464" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-38464"><a href="https://sielc.com/Technology_InorganicAnalysis">Inorganic Analysis</a>
<ul class="sub-menu">
<li id="menu-item-38465" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38465"><a href="https://sielc.com/Technology_AlternativeIonChromatography">Ion Chromatography</a></li>
<li id="menu-item-38466" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38466"><a href="https://sielc.com/Technology_OrganicInorganic">Organic/Inorganic</a></li>
</ul>
</li>
<li id="menu-item-38458" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38458"><a href="https://sielc.com/Technology_RetentionOfPolarCompounds">Polar Compounds</a></li>
<li id="menu-item-3553777" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3553777"><a href="https://sielc.com/prep">Preparative HPLC Service</a></li>
<li id="menu-item-37136" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-37136"><a href="https://sielc.com/Technology_Peptides">Proteins/Peptides</a>
<ul class="sub-menu">
<li id="menu-item-37137" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37137"><a href="https://sielc.com/Technology_Peptides_AlternativeSelectivity">Alternative Selectivity</a></li>
<li id="menu-item-37139" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37139"><a href="https://sielc.com/Technology_Peptides_Digest">Digest</a></li>
<li id="menu-item-37140" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37140"><a href="https://sielc.com/Technology_Peptides_GradientTypes">Gradient Types</a></li>
<li id="menu-item-37141" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37141"><a href="https://sielc.com/Technology_Peptides_Promix">Promix Technology</a></li>
<li id="menu-item-37142" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37142"><a href="https://sielc.com/Technology_Peptides_Selectivity">Selectivity</a></li>
</ul>
</li>
<li id="menu-item-38459" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-38459"><a href="https://sielc.com/Technology_Peptides_Selectivity">Selectivity</a>
<ul class="sub-menu">
<li id="menu-item-3546185" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3546185"><a href="https://sielc.com/technology_2d_properties">2D Properties</a></li>
<li id="menu-item-38461" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38461"><a href="https://sielc.com/Technology_UniqueAdjustableSelectivity">Adjustable Selectivity</a></li>
</ul>
</li>
<li id="menu-item-37126" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-37126"><a href="https://sielc.com/Technology_SmallMolecules">Small Molecules</a>
<ul class="sub-menu">
<li id="menu-item-37127" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37127"><a href="https://sielc.com/Technology_AnionExchange">Anion Exchange</a></li>
<li id="menu-item-37128" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37128"><a href="https://sielc.com/Technology_BLIS">BLIS</a></li>
<li id="menu-item-37129" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37129"><a href="https://sielc.com/Technology_CationExchange">Cation Exchange</a></li>
<li id="menu-item-37130" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37130"><a href="https://sielc.com/Technology_ComplexInteraction">Complex Interaction</a></li>
<li id="menu-item-37131" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37131"><a href="https://sielc.com/Technology_DirectPlasmaAnalysis">Direct Plasma Analysis</a></li>
<li id="menu-item-37132" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37132"><a href="https://sielc.com/Technology_MixedModeSeparation">Mixed-Mode HPLC Separation</a></li>
<li id="menu-item-37133" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37133"><a href="https://sielc.com/Technology_PiPiInteraction">Pi-Pi Interaction</a></li>
<li id="menu-item-37134" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-37134"><a href="https://sielc.com/Technology_Versatility">Universal Phases</a></li>
</ul>
</li>
<li id="menu-item-3538768" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-3538768"><a href="https://sielc.com/Technology_solid-core">Solid-Core</a>
<ul class="sub-menu">
<li id="menu-item-3542347" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3542347"><a href="https://sielc.com/solid-core-primesep-100">Solid-Core Primesep 100</a></li>
<li id="menu-item-3542369" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3542369"><a href="https://sielc.com/solid-core-primesep-s">Solid-Core Primesep S</a></li>
<li id="menu-item-3542384" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3542384"><a href="https://sielc.com/solid-core-primesep-sb">Solid-Core Primesep SB</a></li>
</ul>
</li>
<li id="menu-item-38463" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38463"><a href="https://sielc.com/Technology_SwitchPhase">Switch Phase</a></li>
</ul>
</li>
<li id="menu-item-3560286" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-3560286"><a href="https://sielc.com/services_custom_method_development">Method Development</a>
<ul class="sub-menu">
<li id="menu-item-3560292" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3560292"><a href="https://sielc.com/services_custom_method_development">Custom Method Development by SIELC</a></li>
<li id="menu-item-38585" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38585"><a href="https://sielc.com/technology_methoddevelopment/methoddevelopment_bufferrecommendation">Buffer Recommendation</a></li>
<li id="menu-item-38584" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38584"><a href="https://sielc.com/technology_methoddevelopment/methoddevelopment_columnequilibration">Column Equilibration</a></li>
<li id="menu-item-38578" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38578"><a href="https://sielc.com/MethodDevelopment_ComplexMixture">Complex Mixtures</a></li>
<li id="menu-item-38576" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38576"><a href="https://sielc.com/MethodDevelopment_Guide">Development Guide</a></li>
<li id="menu-item-3480111" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3480111"><a href="https://sielc.com/hplc-simulation">HPLC Simulation</a></li>
<li id="menu-item-38577" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38577"><a href="https://sielc.com/MethodDevelopment_CompoundType">Primesep column selection</a></li>
<li id="menu-item-38467" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38467"><a href="https://sielc.com/stationary-phase-capacity">Stationary phase capacity</a></li>
<li id="menu-item-38587" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38587"><a href="https://sielc.com/USP%20method">USP Methods</a></li>
</ul>
</li>
<li id="menu-item-3463219" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-3463219"><a>Applications</a>
<ul class="sub-menu">
<li id="menu-item-38539" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38539"><a href="https://sielc.com/Applications_By_Compound">By Compound</a></li>
<li id="menu-item-38538" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38538"><a href="https://sielc.com/Applications_By_Column">By Column</a></li>
<li id="menu-item-3557668" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-3557668"><a href="https://sielc.com/uv-vis-spectrum">UV-Vis Spectrum</a></li>
<li id="menu-item-38541" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38541"><a href="https://sielc.com/Applications_By_Detection">By Detection</a></li>
<li id="menu-item-38540" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38540"><a href="https://sielc.com/Applications_By_ApplicationName">By Name</a></li>
<li id="menu-item-38537" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38537"><a href="https://sielc.com/Applications_By_Publish_Date">By Publish Date</a></li>
<li id="menu-item-3556321" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3556321"><a href="https://sielc.com/applications_alltesta">Alltesta/Cromite</a></li>
<li id="menu-item-3500170" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3500170"><a href="https://sielc.com/ai-applications">Artificial intelligence</a></li>
<li id="menu-item-3552850" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-3552850"><a href="/hplc-simulation">HPLC Simulation</a></li>
</ul>
</li>
<li id="menu-item-3463220" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-3463220"><a>Literature</a>
<ul class="sub-menu">
<li id="menu-item-3547026" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3547026"><a href="https://sielc.com/brochures">Brochures</a></li>
<li id="menu-item-3465618" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3465618"><a href="https://sielc.com/cool-applications">Cool Applications</a></li>
<li id="menu-item-38545" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38545"><a href="https://sielc.com/Literature_Newsletters">Newsletters</a></li>
<li id="menu-item-3464311" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-3464311"><a href="/Literature_Publications_Journals">Publications</a>
<ul class="sub-menu">
<li id="menu-item-38550" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38550"><a href="https://sielc.com/Literature_Publications_Conferences">Conferences</a></li>
<li id="menu-item-38549" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38549"><a href="https://sielc.com/literature_publications_journals">Journals</a></li>
</ul>
</li>
<li id="menu-item-38548" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38548"><a href="https://sielc.com/literature_technicalnotes">Technical Notes</a></li>
</ul>
</li>
<li id="menu-item-3463221" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-3463221"><a>FAQ</a>
<ul class="sub-menu">
<li id="menu-item-3547562" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-3547562"><a href="https://sielc.com/bist-ionic-modifier-preparation">BIST Ionic Modifier Preparation</a></li>
<li id="menu-item-38560" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-38560"><a href="https://sielc.com/FAQ_BufferPreparation">Buffer Preparation</a></li>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2025/05/Breaking-New_Cyano-1-150x150.png' alt='SIELC Technologies Nominated for 6 Categories at the Lab Awards 2025!' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/lab-awards-2025-nominations">SIELC Technologies Nominated for 6 Categories at the Lab Awards 2025!</a></p>
</h5>
<p><strong>SIELC Technologies</strong> is honored to be nominated in six categories at the <a href="https://www.labmate-online.com/news/awards2025/198/breaking-news/labmate-awards-2025-voting-open/64705">Lab Awards 2025</a>, recognizing our commitment to innovation and excellence. The nominations highlight our cutting-edge technologies, including Alltesta™ Automated Analyzer, HPLC.cloud, and Cromite™ HPLC System.</p>
<p><strong>Learn more: </strong><a href="https://sielc.com/lab-awards-2025-nominations">Nominated Categories</a></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2025/04/Breaking-New_Cyano-150x150.png' alt='SIELC Presents: Newcrom™ CN2 – Cyano HPLC Column' loading='lazy'></div>
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<h5><p><a href="https://sielc.com/cyano-hplc-column-news">SIELC Presents: Newcrom™ CN2 – Cyano HPLC Column</a></p>
</h5>
<p><strong>SIELC Technologies</strong> presents <a href="https://sielc.com/newcrom-cn2"><strong>Newcrom™ CN2</strong></a> – a versatile cyano-phase HPLC column offering unique selectivity and stable performance across multiple separation modes. It’s an ideal choice when alternative selectivity to traditional C18 and C8 columns is needed.</p>
<p><strong>Learn more:</strong> <a href="https://sielc.com/newcrom-cn2">Newcrom™ CN2</a></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2025/03/Breaking-New_HPLC-Webinar-1-1-150x150.png' alt='SIELC Presents HPLC Webinar 2025 Free Education Series ' loading='lazy'></div>
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<h5><p><a href="https://sielc.com/webinar-2025"><strong>SIELC Presents HPLC Webinar 2025 Free Education Series </strong></a></p>
</h5>
<p>SIELC Technologies is excited to announce the <strong>Chromatography Webinar Series 2025</strong> —a must-attend event for scientists and analysts eager to sharpen their skills in HPLC optimization and mixed-mode techniques.</p>
<p><strong>Learn more:</strong> <a href="https://sielc.com/webinar-2025">HPLC Webinar Education Series</a></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2025/01/Oligo-Brochure-Photo-150x150.png' alt='Introducing BIST™ AC and OligoMg: Next-Gen Oligonucleotide Separation' loading='lazy'></div>
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<h5><p><a href="https://sielc.com/oligonews">Introducing BIST™ AC and OligoMg: Next-Gen Oligonucleotide Separation</a></p>
</h5>
<p>SIELC Technologies presents <a href="https://sielc.com/product/bist-ac">BIST™ AC</a> and <a href="https://sielc.com/product-oligomg">OligoMg</a> columns, revolutionizing oligonucleotide analysis with Bridge Ion Separation Technology (BIST™). These advanced silica-based columns offer high-resolution, selective, and reproducible separation, ensuring precision, efficiency.</p>
<p><strong>Learn more:</strong> <a href="https://sielc.com/wp-content/uploads/2025/01/Oligonucleotides-Analysis-Final.pdf">Oligonucleotides by HPLC</a></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2024/08/SFC_3978-scaled-e1744645283146-150x150.jpg' alt='Introducing the Samplify Automated Sampling System' loading='lazy'></div>
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<h5><p><a href="https://autosampler.cloud/">Introducing the Samplify Automated Sampling System</a></p>
</h5>
<p>We’re thrilled to announce the launch of Samplify, our cutting-edge solution that revolutionizes the sampling process. Designed to enhance efficiency, Samplify automates sample preparation, ensuring consistent and accurate results while reducing human error. With its intuitive interface and customizable features, it’s the perfect addition to any laboratory looking to optimize workflow and productivity.</p>
<p>Learn more about how Samplify can transform your sampling experience by visiting <a href="https://autosampler.cloud/">Samplify</a>.</p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2022/12/Screenshot-from-2022-12-13-16-42-13-150x150.png' alt='Primesep Column Selection' loading='lazy'></div>
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<h5><p><a href="https://sielc.com/MethodDevelopment_CompoundType">Primesep Column Selection</a></p>
</h5>
<p>Use this tool to narrow down your Primesep column selection by your analyte’s properties.</p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2024/12/Lipak-150x150.png' alt='Transforming Lipid Analysis with Innovation' loading='lazy'></div>
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<h5><p><a href="https://sielc.com/lipids">Transforming Lipid Analysis with Innovation</a></p>
</h5>
<p>Accurate, Reliable, and Simplified<br />
Imagine achieving unparalleled resolution and precision in lipidomics with a single column that accommodates the diverse polarities of lipid species. The Lipak™ column redefines lipid analysis, offering a simplified yet robust solution for separating both polar and nonpolar lipid classes with unmatched efficiency.</p>
<p><strong>Learn more</strong>: <a href="https://sielc.com/wp-content/uploads/2024/12/Lipids-Analysis.pdf">Lipids by HPLC</a></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2022/05/Bridge-150x150.jpg' alt='BIST™ – a New Mode of LC Separation' loading='lazy'></div>
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<h5><p><a href="bridge-ion-separation-technology-or-bist">BIST™ – a New Mode of LC Separation</a></p>
</h5>
<p>Bridge Ion Separation Technology, or BIST™, is a brand new LC separation technique developed by SIELC. The goal of BIST™ is simple – expand the scope of HPLC applications.</p>
<p><a href="https://www.youtube.com/watch?v=qXBXDv0R6c0" target="_blank" rel="noopener"><br />
<b>Watch how it works</b></a></p>
<div style="height: 20px;"></div>
<p>BIST™ from SIELC Technologies is a new and simple way to achieve many separations that are traditionally difficult or impossible to achieve with any other HPLC columns currently on the market! In short, BIST™ is complex chromatography without the hassle.</p>
<p>BIST™ provides an additional separation tool for a whole class of organic and inorganic charged molecules. BIST™ columns, simple mobile phases, and an array of applications provide a whole new continent on the chromatography map.</p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2022/04/Alltesta-PPAVD-14-150x150.jpg' alt='Innovative HPLC Systems & Devices by SIELC Technologies' loading='lazy'></div>
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<h5><p><a href="https://sielc.com/devices">Innovative HPLC Systems & Devices by SIELC Technologies</a></p>
</h5>
<p><span style="color: #000000;">SIELC Technologies offers several innovative HPLC Systems & devices often used in chromatography applications to add special capabilities. These devices include:</span></p>
<ul>
<li><span style="font-weight: 400;"> </span><a href="https://sielc.com/product/alltesta-isocratic-automated-analyzer"><b>The Alltesta™ Isocratic Analyzer</b></a></li>
<li><a href="https://sielc.com/alltesta-gradient-automated-analyzer"><b>The Alltesta™ Gradient Analyzer</b></a></li>
<li><a href="https://sielc.com/alltesta-cromite-analyzer"><b>The Cromite™ HPLC System</b></a></li>
<li><a href="https://sielc.com/samplify-automated-sampling-system"><b>The Samplify™ Automated Sampling System</b></a></li>
<li><a href="https://sielc.com/product/alltesta-autosampler"><b>Alltesta™ Mini Autosampler</b></a></li>
<li><a href="https://sielc.com/product/alltesta-high-pressure-switching-valve"><b>Alltesta™ Mini High-Pressure Switching Valve</b></a></li>
<li><a href="https://sielc.com/product/alltesta-syringe-pump"><b>Alltesta™ Mini Syringe Pump</b></a></li>
<li><a href="https://sielc.com/product/alltesta-mini-uv-vis-detector"><b>Alltesta™ Mini UV/Vis Detector</b></a></li>
</ul>
<p>All Our Solutions in One Catalog: <a href="https://sielc.com/wp-content/uploads/2025/03/Product-catalog_SIELC.pdf">Advanced HPLC Systems & Devices by SIELC</a></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/FlipLC_Animated-150x150.gif' alt='FlipLC™' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/Technology_FlipLC">FlipLC™</a></p>
</h5>
<p><span style="font-weight: 400; color: #000000;">Samples from natural sources, such as fruits, vegetables, culinary products, water, soil, and bodily fluids, are complex mixtures containing dozens, or even hundreds, of compounds. Our FlipLC method removes impurities from these complex samples, shortens chromatography run time, and increases the column lifetime. It requires minimal sample preparation. The isolation column flips direction and position in the flow path during this process, and thus we have the name FlipLC.</span></p>
</div>
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<div class='home_product_category row_12'>
<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/NewcromKB-150x150.jpg' alt='Newcrom' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/newcrom">Newcrom</a></p>
</h5>
<p><span style="color: #000000;">Newcrom is an advanced column format with a new inner/outer design. This column and the corresponding adapter entirely eliminate the need for any high-pressure fittings or tubing, as well as minimizing all possible dead volumes. Furthermore, if a leak ever occurs in the high-pressure column inlet, the mobile phase is contained within the column adapter (no external leakage). <a style="color: #000000;" href="https://www.sielc.com/newcrom.html">Read more.</a></span></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/products20120614123034368054436.gif' alt='SHARC ™' loading='lazy'></div>
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<h5><p><a href="https://sielc.com/Products_Sharc">SHARC ™</a></p>
</h5>
<p><span style="color: #000000;">SHARC™ HPLC columns are the latest innovative columns from SIELC Technologies, the inventors of Primesep®. SHARC™ columns are the first commercially available columns with separation based primarily on hydrogen bonding. SHARC stands for <strong>S</strong>pecific <strong>H</strong>ydrogen-bond <strong>A</strong>dsorption <strong>R</strong>esolution <strong>C</strong>olumn. Hydrogen bonding is an interaction (attraction) between hydrogen atoms bonded to an electronegative atom (i.e. oxygen, nitrogen, fluorine) and similarly electronegative atoms on different molecules.</span></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/products201010281657217477.gif' alt='Primesep ®' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/wp-content/uploads/2022/02/Primesep-100-02.04.22.pdf">Primesep ®</a></p>
</h5>
<p><span style="color: #000000;">Primesep</span> <a href="https://sielc.com/Technology_NovelStationaryPhases">stationary phases</a> <span style="color: #000000;">offer unprecedented selectivity in the separation of a broad array of</span> <a href="https://sielc.com/Applications_By_Compound">chemical compounds,</a> <span style="color: #000000;">and in</span> <a href="https://sielc.com/Applications_By_ApplicationName">multiple applications</a><span style="color: #000000;">. A wide range of HPLC columns with I.D.’s from 0.5 mm to 22 mm are available. Corresponding</span> <a href="https://www.sielc.com/Products_Primesep.html">Primesep</a> <span style="color: #000000;">guard columns are available for all stationary phases and do not require holders. SIELC offers a</span> <a href="https://sielc.com/Services_MethodDevelopment">method development</a> <span style="color: #000000;">service which is available for all customers. Ask about our special</span> <a href="https://sielc.com/Services_CustomPhases">custom HPLC phases</a> <span style="color: #000000;">tailored for specific separations.</span></p>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/products2010102817084914873.gif' alt='Obelisc ™' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/Products_Obelisc">Obelisc ™</a></p>
</h5>
<p><span style="color: #000000;">Two complimentary columns, Obelisc R and Obelisc N, based on <strong>Li</strong>quid <strong>S</strong>eparation <strong>C</strong>ell (</span> <a href="https://sielc.com/Technology_LISC">LiSC</a> <span style="color: #000000;">™) technology, offer a new approach to separate a variety of small molecules. Buffer concentration, buffer pH, and organic modifier concentration are three orthogonal parameters of the mobile phase that allow adjustment of column properties to separate complex mixtures.</span></p>
</div>
</div>
<div class='home_product_category row_16'>
<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/Promix_image.gif' alt='Promix ™' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/Technology_Peptides_Promix">Promix ™</a></p>
</h5>
<p><a href="https://sielc.com/Technology_Peptides_Promix">Promix</a><span style="color: #000000;"> is an</span> <a href="https://sielc.com/Technology_Peptides_AlternativeSelectivity">alternative chromatography</a> <span style="color: #000000;">technology for efficient resolution of peptides and proteins. The technology is based on a combination of two interactions – hydrophobic and ionic. This approach is possible due to a new type of separation medium: a chemical</span> <a href="https://sielc.com/Technology_Peptides_GradientTypes">combination of hydrophobic and ionic functional groups</a><span style="color: #000000;">, on a ligand bonded to a silica support. With this phase, unparalleled selectivity and</span> <a href="https://www.sielc.com/Technology_Peptides_Digest.html">peak capacity</a> <span style="color: #000000;">can be achieved. Independent adjustment of the amount of buffer and organic modifier creates an</span> <a href="https://sielc.com/Technology_Peptides_Digest">infinite number of separation conditions</a><span style="color: #000000;">, that are suitable for many types of bio-molecules.</span></p>
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<div class='home_product_category row_17'>
<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/products20110429074649408744251.gif' alt='Legacy ™' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/Products_Legacy">Legacy ™</a></p>
</h5>
<p><span style="color: #000000;">SIELC offers “Legacy” columns. These columns support historical and current USP-validated methods.</span></p>
<p>Four types of USP Specifications are offered: Legacy L1, Legacy L3, Legacy L8, Legacy L16.</p>
</div>
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<div class='home_product_category row_18'>
<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/products201010281714266206.gif' alt='HPLC Hardware' loading='lazy'></div>
<div class='description'>
<h5><p><a href="https://sielc.com/Column_Hardware">HPLC Hardware</a></p>
</h5>
<ul>
<li><span style="color: #000000;">SIELC Technologies offers a patented design of capillary, analytical, and preparative hardware for HPLC.</span></li>
<li><span style="color: #000000;">Unified cylindrical shape of the columns is a signature hardware style developed and produced by SIELC.</span></li>
<li><span style="color: #000000;">Superior performance, distinguished look, and reduced hardware costs are just a few benefits of the new design.</span></li>
</ul>
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<div class='img_container'><img src='https://sielc.com/wp-content/uploads/2015/11/products201010281724268019.gif' alt='Fittings' loading='lazy'></div>
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